有机药学与制药Organic Medicinal and Pharmaceutical fb2 pdf azw3 网盘 rtf 免费 下载 txt

For over half a century, this book has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Eleventh Edition, coverage begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications.

Preface

Contributors

CHAPTER 1 Introduction

CHAPTER 2 Physicochemical Properties in Relation to Biological Action

CHAPTER 3 Combinatorial Chemistry

CHAPTER 4 Metabolic Changes of Drugs and Related Organic Compounds

CHAPTER 5 Prodrugs and Drug Latentiation

CHAPTER 6 Biotechnology and Drug Discovery

CHAPTER 7 Immunobiologicals

CHAPTER 8 Anti-infective Agents

CHAPTER 9 Antimalarials

CHAPTER 10 Antibacterial Antibiotics

CHAPTER 11 Antiviral Agents

CHAPTER 12 Antineoplastic Agents

CHAPTER 13 Agents for Diagnostic Imaging

CHAPTER 14 Central Nervous System Depressants

CHAPTER 15 Central Nervous System Stimulants

CHAPTER 16 Adrenergic Agents

CHAPTER 17 Cholinergic Drugs and Related Agents

CHAPTER 18 Diuretics

CHAPTER 19 Cardiovascular Agents

CHAPTER 20 Local Anesthetic Agents

CHAPTER 21 Histamine and Antihistaminic Agents

CHAPTER 22 Analgesic Agents

CHAPTER 23 Steroids and Therapeutically Related Compounds

CHAPTER 24 Prostaglandins, Leukotrienes, and Other Eicosanoids

CHAPTER 25 Proteins, Enzymes, and Peptide Hormones

CHAPTER 26 Vitamins and Related Compounds

CHAPTER 27 An Introduction to the Medicinal Chemistry of Herbs

CHAPTER 28 Computational Chemistry and Computer-Assisted Drug Design

App Calculated Log P, Log D, and pK[subscript al

Index

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书籍介绍

For over half a century, this book has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Eleventh Edition, coverage begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications